Web2. dec 2024 · A tentative interpretation of the TOPCAT trial based on randomized evidence from the brain natriuretic peptide stratum analysis. Eur J Heart Fail. 2016; 18:1411–1414. doi: 10.1002/ejhf.621 Crossref Medline Google Scholar; 28. Lund LH, Oldgren J, James S. Registry-based pragmatic trials in heart failure: current experience and future directions. WebPred 1 dňom · The DOHAS (Dialysis Outcomes Heart Failure Aldactone Study) trial, a prospective, multicenter, randomized controlled, open-label trial in 5 Japanese centers, investigated the use of spironolactone in oligoanuric hemodialysis patients versus a control group. ... The TOPCAT trial (Spironolactone for Heart Failure with Preserved Ejection …
Treatment of Preserved Cardiac Function Heart Failure With an ...
Web6. jan 2015 · Background: Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) patients with heart failure and preserved left … Web15. okt 2004 · This study is a randomized clinical trial of a novel therapeutic approach, specifically the use of spironolactone, an aldosterone antagonist, in treating these … destiny 2 season 15 gambit weapons
A tentative interpretation of the TOPCAT trial based on …
Web4. apr 2024 · Regional Discrepancies in the Reported Use and Actual Use of Spironolactone among Repository Participants in the TOPCAT Trial. The repository participants included … The trial was designed to have 80% power to detect a 20% relative reduction from a 3-year primary outcome rate of 17.4%, with an overall type I error of 0.05 (two-sided test). After accounting for interim monitoring (see the Methods section in the Supplementary Appendix), we calculated that data on 551 … Zobraziť viac Many patients with heart failure have a normal or near-normal left ventricular ejection fraction.1-4 Such patients share common signs … Zobraziť viac We designed a phase 3, multicenter, international, randomized, double-blind, placebo-controlled trial. The trial was sponsored by the … Zobraziť viac Among patients with heart failure and a reduced ejection fraction and those with myocardial infarction complicated by heart failure and left … Zobraziť viac Patients 50 years of age or older were eligible if they provided written informed consent and had at least one sign and at least one symptom of heart failure on a prespecified list of clinically defined signs and symptoms, a … Zobraziť viac Webthe TOPCAT trial (n5205). Associations were validated in a participant-level meta-analysis (n5810) that included participants with HFpEF from the PHFS study (United ... heart failure with preserved ejection fraction: detailed phenotypes, prognosis, and response to spironolactone. JACC Heart Fail 2024;8: 172-184. DOI: 10.1016/j.jchf.2024.09.009. chudy disney