WebNov 1, 2007 · It was found that cryptotanshinone inhibited the STAT3 tyrosine phosphorylation in DU145 prostate cancer cell in a dose-dependent manner. However, the … Web2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ...
Cryptotanshinone - an overview ScienceDirect Topics
WebCryptotanshinone: A review of its pharmacology activities and molecular mechanisms. As a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received … WebNov 1, 2024 · To illustrate the synergistic antitumor effects of Cryptotanshinone and Paclitaxel on the expression of factors and proteins involving in cell apoptosis, cell cycle and metastasis induced by Cryptotanshinone and Paclitaxel, we detected the expression of STAT3, p-STAT3 (Try705), p-STAT3 (Ser727), Bcl-2, CDK2, MMP2, E-cadherin and β … list intstream
Tanshinone I - an overview ScienceDirect Topics
WebFeb 8, 2024 · In conclusion, while STAT3 regulates matrix metalloproteinase-9 and connective tissue growth factor expression in diabetic rats with cardiac fibrosis, cryptotanshinone inhibited fibrosis to improve cardiac function by suppressing the STAT3 pathway. Cryptotanshinone is suitable as an alternative remedy for therapy of cardiac … WebJun 8, 2016 · -Methoxydalbergione (4-MD) -Curcumin -Thymoquinone (TQ) INHIBITION OF STAT3 ACTIVITY BY PHOSPHATASES -Acetoxychavicol acetate (ACA) -Guggulsterone (GS) -Hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) -Farnesol (FOH) -Capillarisin (CPS) MODULATION OF STAT3 ACTIVITY THROUGH ROS -Nimbolide (NL) -Shogaol (6SG) … WebApr 18, 2024 · Cryptotanshinone (CTs), one of the major tanshinones isolated from the root of SM, is a kind of lipophilic compound and can pass through BBB ( 9, 10 ). CTs has various biological activities, such as anti-oxidation, anti-inflammation, anti-tumor, anti-apoptosis, anti-platelet aggregation activities, and so on ( 11 – 14 ). list int sort descending c#